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Major PTM features found in mature lanthipeptide. Didehydrobutyrine (Dhb) is derived from threonine and didehydroalanine (Dha) from serine. Thioether cross-linking between Dhb and cysteine results in methyllanthionine while that between Dha and cysteine gives lanthionine. The abbreviations Xn and Xn’ represent peptide sequences
