Table 2.
Selected lanthipeptides, production method and current concentration range recorded for each designated method
| Lanthipeptide | Attainable [product] (mg L−1) | |||||
|---|---|---|---|---|---|---|
| Native producer (mg/l) | Ref. | Optimized native producer (mg/l) | Ref. | External host (mg/l) | Ref. | |
| Nisin | 0.178 | [95]a | 1.09 | [95]a | 24 | [96] |
| Lichenicidins | ND | ND | 6 | [19] | ||
| Prochlorosins | 5.0 × 10−4 | [96] | ND | 1–3.5 | [96] | |
| Epilancin 15X | 0.5 | [97] | 3.0 | [98] | ND | |
| Epidermin | 20 | [99] | 1000 | [99] | ND | |
| Gallidermin | 5.0 | [100] | 720, 200 | [90, 101] | ND | |
| Nukacin ISK-1 | 1.06 | [102] | ND | 1.5 | [103] | |
| Ala(0)actagardine | 6.85 | [104] | ND | 4.2 | [105] | |
| Mutacin 1140 | 0.1 | [91] | 50, 10 | [91, 106] | ND | |
| Lacticin 481 | 0.6 | [107] | 1.1 | [108] | ND | |
| Lacticin 3147 | 1.0 | [109] | ND | ND | ||
Values were obtained from previous experiments, with special emphasis on their highest recorded yield. Entries in italic indicate yields obtained from engineering growth media to reduce cost
ND data not described
avalue converted to mg L−1 using International Unit Converter (http://www.etoolsage.com/converter/IU_Converter.asp)