Table 5.

The effects of datasets, algorithm, and the definition of RBRs on the prediction performance of our method

Cutoff (Dataset, algorithm)	SN	SP	PPV	ACC	F-score	MCC
5 Å (RB195, RF)	0.720	0.892	0.550	0.867	0.616	0.546
5 Å (RB138, RF)	0.678	0.910	0.568	0.876	0.618	0.547
5 Å (RB138, SVM)	0.621	0.900	0.531	0.858	0.566	0.485
3.5 Å (RB138, RF)	0.670	0.937	0.525	0.912	0.588	0.545
3.5 Å (RB138, SVM)	0.630	0.908	0.415	0.882	0.500	0.449