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. 2016 Jun 7;23:48. doi: 10.1186/s12929-016-0265-0

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — The predicted targets of hsa-miR-138 and hsa-miR-409 were reduced examined by real-time PCR. The selected mRNA level was tested in fetal hippocampus tissues of DS and control group. All the selected mRNA was reduced in DS group compared to control group. The mRNAs expression was normalized to GAPDH. The expression of EZH2, NNAT, SMARCC1, MAML1 and SOX11 showed significant difference between two groups. The asterisks indicate the statistically significant difference