Table 2.
Oxidative stress marker levels and antioxidant enzyme activities in each group
| Parameters | Control group | PbAc group | IOLE group | IOLE + PbAc group |
|---|---|---|---|---|
| LPO (nmol/mg protein) | 1.23±0.17 | 1.91±0.11a | 1.16±0.12 | 1.29±0.15b |
| NO (µmol/mg protein) | 1.68±0.12 | 2.23±0.16a | 1.48±0.14a | 1.81±0.13b |
| GSH (mmol/mg protein) | 0.32±0.02 | 0.26±0.01a | 0.39±0.02 | 0.29±0.02b |
| SOD (U/mg protein) | 923.5±83.6 | 687.3±54.9a | 1,068.4±98.3a | 836.7±62.4b |
| CAT (U/mg protein) | 0.41±0.02 | 0.29±0.02a | 0.44±0.01 | 0.38±0.02b |
| GPx (µmol/mg protein) | 0.68±0.03 | 0.51±0.03a | 0.72±0.04 | 0.61±0.03b |
| GR (µmol/mg protein) | 8.5±0.03 | 4.8±0.02a | 8.9±0.05 | 6.8±0.03a,b |
Notes: Values are given as mean ± SEM (n=7).
a
P<0.05, significant change with respect to control;
b
P<0.05, significant change with respect to PbAc for Duncan’s post hoc test.
Abbreviations: CAT, catalase; GPx, GSH peroxidase; GR, GSH reductase; GSH, glutathione; IOLE, Indigofera oblongifolia leaf extract; LPO, lipid peroxidation; NO, nitric oxide; PbAc, lead acetate; SEM, standard error of the mean; SOD, superoxide dismutase.