Table 1.

Patient Characteristics.

Patient Number	Diagnosis	Gender	Indication for Transplant	Infections pre-HSCT	Age at Transplant	Donor	Conditioning Regimen
1	IPEX	Male	PID with severe eczema/allergies, enteropathy with TPN dependence, and FTT		10 months	Haplo related	Alem, Flu, Cy, Mel, TBI
2	Birc4/XIAP deficiency	Male	HLH		11 months	Haplo related	Alem, Flu, Mel, TBI
3	DKC	Female	BMF		19 years	10/10 MUD	Alem, Flu, TBI
4	CGD	Male	PID; brother with life-threatening infections		5 months	10/10 MUD	Alem, Flu, Mel
5	CGD	Male	PID with life-threatening infections, enteritis, FTT	Klebsiella pneumonia, Paecilomyces pneumonia	5 years	Haplo related	Alem, Flu, Mel, TBI
6	DKC	Male	BMF		14 years	10/10 MUD	Alem, Flu, TBI
7	CGD	Male	PID with life-threatening infections; enteritis, FTT	MRSA bacteremia, fungal pneumonia	8 years	10/10 MUD	Alem, Flu, Bu
8	Hyper IgM	Male	LPD		12 years	10/10 MUD	Alem, Flu, Mel, TBI
9	DBA	Male	Steroid refractory		3 years	10/10 MUD	Alem, Flu, Mel
10	HLH	Female	Chemotherapy refractory		21 years	5/8 MMUD	Alem, Flu, Mel, TBI
11	GT	Female	Platelet-refractory bleeding		8 years	Haplo related	Alem, Flu, Mel

Alem, alemtuzumab, BMF, bone marrow failure; Bu, busulfan; CGD, chronic granulomatous disease; Cy, cyclophosphamide, DBA Diamond-Blackfan anemia; DKC, dyskeratosis congenita; Flu, fludarabine; FTT, failure to thrive; GT, Glanzmann’s thrombasthenia; HLH, hemophagocytic lymphohistiocytosis; HSCT, hematopoietic stem cell transplant; IPEX, immune dysregulation polyendocrinopathy X-linked; LPD, lymphoproliferative disease; Mel, melphalan; MMUD mismatched unrelated donor; MRSA, methicillin-resistant staphylococcus aureus; MUD, matched unrelated donor; PID, primary immunodeficiency; TBI, total body irradiation; TPN, total parenteral nutrition.