Table 1.

Evolution of thyroid function and autoimmunity in patient.

Date	Clinical status	FT4 (pmol/L)	FT3 (pmol/L)	TSH (U/L)	TRAbs (U/L)
06/07/2010	Onset of ophthalmopathy	11.6	5.43	1.49	0.2
24/09/2012	Onset of hyperthyroidism	16.6	9.56	0.04	7.6
11/05/2013	During thionamide treatment	10.9	4.8	3.33	0.3
14/07/2014	After thionamide treatment	11	5.4	2.96	0.1

Reference ranges: FT4, 11.0–23.0 pmol/L; FT3, 2.67–7.03 pmol/L; TSH, 0.4–4.5 U/L; TRAbs <0.1 U/L. The patient had normal thyroid function and negative TRAbs at the onset of ophthalmopathy, but developed thyroid dysfunction with TRAb positivity 24 months after the initial presentation. TRAb levels returned to normal following treatment with thionamides.