Figure 3. Effects of CHC on metabolic substrate transport into cells.
Cellular consumption of glucose (A) and pyruvate (B) from the media after exposure to increasing concentrations of CHC (50–500 µM) was determined in MCF7 cells. Lactate production from cells was assessed under the same experimental conditions (C). Glucose, pyruvate, and lactate levels in media were determined before and after 4 h incubation with cells. Values were normalized to total cell number/well and represent means ± SEM, n=3–5. * p < 0.05 compared to control. N.S. denotes no significant difference between groups.