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Systolic blood pressure and proteinuria during pregnancy. (A) Systolic blood pressure was not significantly different between ANP+/+ (n = 5) and ANP−/− (n = 5) dams either pre-pregnancy (non-pregnant; NP) or at E12.5 or E17.5 by two-way ANOVA. Systolic blood pressure did not increase in pregnancy in either genotype. Data are mean ± SD. (B) ANP−/− mice did not demonstrate proteinuria at E18.5. Lines represent median, n = 7–8.
