Table S1.
Comparison of clinical and patient-reported outcomes at baseline: subjects who transitioned into the FM+CWP+ group versus subjects who remained in the FM−CWP− and FM−CWP+ groups at follow-up
| Outcome, mean (SD) | FM−CWP− → FM−CWP− (n=55) | FM−CWP− → FM+CWP+ (n=2) | FM−CWP+ → FM−CWP+ (n=42) | FM−CWP+ → FM+CWP+ (n=8) |
|---|---|---|---|---|
| Number of comorbidities | 1.1 (1.18) | 2.0 (1.41) | 3.1 (1.92) | 3.9 (1.89) |
| Among those with ≥1a | 1.9 (0.91) | 2.0 (1.41) | 3.3 (1.83) | 3.9 (1.89) |
| BPI-SF Pain Severity Indexb,c | 2.5 (2.16) | 2.9 (0.18) | 4.2 (1.96) | 4.6 (1.40) |
| Pain at worst, past 24 hours | 3.4 (2.52) | 3.0 (1.41) | 5.4 (2.34) | 6.0 (2.00) |
| Pain at least, past 24 hours | 1.5 (2.14) | 2.5 (0.71) | 2.8 (2.19) | 3.0 (1.20) |
| Average pain | 3.2 (2.43) | 3.0 (0.00)d | 4.5 (1.84) | 4.9 (1.13) |
| Pain right now | 1.8 (2.38) | 3.0 (0.00)d | 4.2 (2.39) | 4.5 (1.85) |
| BPI-SF Pain Interference Indexb,c | 1.8 (2.33) | 2.6 (0.71) | 4.0 (2.65) | 5.3 (1.80) |
| General activity | 1.9 (2.61) | 2.5 (0.71) | 4.2 (2.90) | 5.0 (1.93) |
| Mood | 2.1 (2.71) | 2.0 (1.41) | 3.6 (3.02) | 6.3 (2.82) |
| Walking ability | 1.6 (2.42) | 2.0 (0.00) | 4.2 (3.08) | 4.4 (2.72) |
| Normal work | 1.7 (2.69) | 2.5 (0.71) | 4.3 (3.01) | 5.0 (2.07) |
| Relations with other people | 1.1 (2.19) | 1.0 (1.41) | 2.9 (2.97) | 4.4 (3.16) |
| Sleep | 2.1 (2.61) | 5.0 (1.41) | 4.2 (3.40) | 6.3 (1.98) |
| Enjoyment of life | 2.0 (2.75) | 3.5 (2.12) | 4.5 (3.22) | 5.9 (2.85) |
| MOS-SS Overall Sleep Problem Indexc | 27.2 (16.44) | 42.2 (4.71) | 43.3 (16.25) | 54.0 (16.00) |
| SF-12v2e | ||||
| Physical Component Summary | 51.9 (7.45) | 42.7 (3.56) | 38.8 (10.96) | 36.6 (8.47) |
| Mental Component Summary | 51.7 (8.82) | 48.1 (7.89) | 45.6 (12.52) | 45.9 (10.85) |
| Physical function | 87.3 (20.90) | 50.0 (0.00)d | 53.0 (31.82) | 43.8 (34.72) |
| Role physical | 84.3 (21.28) | 68.8 (8.84) | 50.3 (28.09) | 51.6 (28.69) |
| Bodily pain | 84.5 (18.94) | 75.0 (0.00)d | 53.6 (26.81) | 46.9 (20.86) |
| General health | 78.9 (16.35) | 60.0 (0.00)d | 52.7 (22.34) | 53.1 (25.49) |
| Vitality | 62.7 (17.92) | 37.5 (17.68) | 37.5 (22.93) | 31.3 (29.12) |
| Social functioning | 91.8 (17.38) | 75.0 (0.00)d | 70.2 (27.74) | 65.6 (29.69) |
| Role emotional | 88.2 (19.31) | 68.8 (8.84) | 69.6 (27.77) | 70.3 (26.67) |
| Mental health | 74.3 (18.70) | 75.0 (17.68) | 59.8 (24.31) | 60.9 (15.58) |
Notes:
Among those with at least one reported comorbidity (n=33 for FM−CWP− → FM−CWP−; n=2 for FM−CWP− → FM+CWP+; n=40 for FM−CWP+ → FM−CWP+; n=8 for FM−CWP+ → FM+CWP+).
Only subjects experiencing pain or tenderness in the last week answered this series of questions, and the results presented in this table are based on these counts: number experiencing pain or tenderness over past week (n=37 for FM−CWP− → FM−CWP−; n=2 for FM−CWP− → FM+CWP+; n=42 for FM−CWP+ → FM−CWP+; n=8 for FM−CWP+ → FM+CWP+).
Higher scores indicate worse outcomes.
SD is 0 because both subjects had the same score.
Higher scores indicate better outcomes.
Abbreviations: BPI-SF, Brief Pain Inventory –Short Form; CWP+, chronic widespread pain – positive; CWP−, chronic widespread pain – negative; FM+, diagnosed with fibromyalgia; FM−, not diagnosed with fibromyalgia; MOS-SS, Medical Outcomes Study – Sleep Scale; SF-12v2, 12-Item Short-Form Health Survey, Version 2.