Abstract
A patient had neuropsychological testing during, and at two days and seven weeks after a transient global amnesia (TGA) attack. During the attack she exhibited a characteristically profound anterograde amnesia but a limited remote memory loss; the most striking impairment was a deficit in personal episodic memory revealed by her performance on the Autobiographical Memory Interview. Personal and general semantic information was less impaired although there were indications of a temporal gradient in the impairment. When tested after the attack, she demonstrated normal anterograde and retrograde memory. A SPECT scan performed during TGA showed a focal reduction in cerebral perfusion in the postero-medial temporal lobes bilaterally which had resolved after seven weeks.
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- Cermak L. S., O'Connor M. The anterograde and retrograde retrieval ability of a patient with amnesia due to encephalitis. Neuropsychologia. 1983;21(3):213–234. doi: 10.1016/0028-3932(83)90039-8. [DOI] [PubMed] [Google Scholar]
- Gallassi R., Lorusso S., Stracciari A. Neuropsychological findings during a transient global amnesia attack and its follow-up. Ital J Neurol Sci. 1986 Feb;7(1):45–49. doi: 10.1007/BF02230416. [DOI] [PubMed] [Google Scholar]
- Goldenberg G., Podreka I., Pfaffelmeyer N., Wessely P., Deecke L. Thalamic ischemia in transient global amnesia: a SPECT study. Neurology. 1991 Nov;41(11):1748–1752. doi: 10.1212/wnl.41.11.1748. [DOI] [PubMed] [Google Scholar]
- Hodges J. R., Ward C. D. Observations during transient global amnesia. A behavioural and neuropsychological study of five cases. Brain. 1989 Jun;112(Pt 3):595–620. doi: 10.1093/brain/112.3.595. [DOI] [PubMed] [Google Scholar]
- Hodges J. R., Warlow C. P. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):834–843. doi: 10.1136/jnnp.53.10.834. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kopelman M. D., Wilson B. A., Baddeley A. D. The autobiographical memory interview: a new assessment of autobiographical and personal semantic memory in amnesic patients. J Clin Exp Neuropsychol. 1989 Oct;11(5):724–744. doi: 10.1080/01688638908400928. [DOI] [PubMed] [Google Scholar]
- Kritchevsky M., Squire L. R. Transient global amnesia: evidence for extensive, temporally graded retrograde amnesia. Neurology. 1989 Feb;39(2 Pt 1):213–218. doi: 10.1212/wnl.39.2.213. [DOI] [PubMed] [Google Scholar]
- Kritchevsky M., Squire L. R., Zouzounis J. A. Transient global amnesia: characterization of anterograde and retrograde amnesia. Neurology. 1988 Feb;38(2):213–219. doi: 10.1212/wnl.38.2.213. [DOI] [PubMed] [Google Scholar]
- McCarthy R. A., Warrington E. K. Actors but not scripts: the dissociation of people and events in retrograde amnesia. Neuropsychologia. 1992 Jul;30(7):633–644. doi: 10.1016/0028-3932(92)90068-w. [DOI] [PubMed] [Google Scholar]
- Regard M., Landis T. Transient global amnesia: neuropsychological dysfunction during attack and recovery in two "pure" cases. J Neurol Neurosurg Psychiatry. 1984 Jul;47(7):668–672. doi: 10.1136/jnnp.47.7.668. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Stillhard G., Landis T., Schiess R., Regard M., Sialer G. Bitemporal hypoperfusion in transient global amnesia: 99m-Tc-HM-PAO SPECT and neuropsychological findings during and after an attack. J Neurol Neurosurg Psychiatry. 1990 Apr;53(4):339–342. doi: 10.1136/jnnp.53.4.339. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tanabe H., Hashikawa K., Nakagawa Y., Ikeda M., Yamamoto H., Harada K., Tsumoto T., Nishimura T., Shiraishi J., Kimura K. Memory loss due to transient hypoperfusion in the medial temporal lobes including hippocampus. Acta Neurol Scand. 1991 Jul;84(1):22–27. doi: 10.1111/j.1600-0404.1991.tb04897.x. [DOI] [PubMed] [Google Scholar]