Fig. 3.

Effect of RDN on endothelial function. a Endothelium-dependent vasorelaxation of aortic rings in response to carbachol and b endothelium-independent relaxation in response to glyceryl trinitrate in 16 weeks old SD-sham, SD-RDN, ApoE^−/−-sham and ApoE^−/−-RDN rats. Values are mean ± SEM. ^§p < 0.001 SD-RDN vs. ApoE^−\−-RDN and ApoE^−\−-sham; ^ψp < 0.001 SD-sham vs. ApoE^−\−-RDN;#p < 0.01 SD-sham vs. ApoE^−\−-RDN; ^θp < 0.001 SD-sham vs. ApoE^−\−-sham; *p < 0.01 ApoE^−\−-RDN vs. ApoE^−\−-sham (two-way-Anova followed by Bonferroni multiple comparison test)