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. 2016 Jun 8;14:13. doi: 10.1186/s13053-016-0053-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — LOH analysis of DNA from the p.Leu139Pro variant carrier. DNA was purified from blood and tumor samples from the patient and SDHB exon 4 was amplified using intronic primer pairs flanking exon 4 and sequenced. DNA sequences from blood (a) and from tumor tissue (b) are shown. The SDHB c.416T > C, p.Leu139Pro position is indicated by an arrow