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. 2016 Jun 1;9:3299–3305. doi: 10.2147/OTT.S102351

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© 2016 Qiao et al. This work is published and licensed by Dove Medical Press Limited

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The correlation of variation in serum MMP-9 levels and response to chemotherapy in patients with advanced NSCLC.

Notes: Serum MMP-9 levels increased in patients with NSCLC who developed PD and decreased in patients who developed CR/PR/SD. The difference was statistically significant. (A) The variation in serum MMP-9 levels in patients with different curative effects after one cycle. (B) The variation in serum MMP-9 levels in patients with different curative effects after two cycles. (C) The variation in serum MMP-9 levels in patients with different curative effects after four cycles. ^*P<0.05 and ^**P<0.01. Each dot represents a patient and the red lines represent the median values.

Abbreviations: MMP-9, matrix metalloproteinase 9; NSCLC, non-small-cell lung cancer; PD, progressive disease; CR, complete response; PR, partial response; SD, stable disease.