Table 2.
Comparison of the median serum CXCR4 levels according to clinical features
| Variables | No of patients (N=55) | Median CXCR4 level (pg/mL) | P-value |
|---|---|---|---|
| Age, median (range) (years) | 62 (39–82) | ||
| ≤65 | 40 | 277.36 | 0.424 |
| >65 | 15 | 271.05 | |
| Sex | |||
| Male | 35 | 246.29 | 0.351 |
| Female | 20 | 326.40 | |
| Disease status | |||
| Metastatic | 47 | 271.76 | 0.467 |
| Recurrent | 8 | 273.67 | |
| Palliative surgery | |||
| Yes | 36 | 250.33 | 0.502 |
| No | 19 | 301.05 | |
| Primary site | |||
| Colon | 39 | 310.74 | 0.646 |
| Rectum | 16 | 287.55 | |
| No of metastatic sites | |||
| 0–1 | 13 | 224.86 | 0.011 |
| ≥2 | 42 | 315.10 | |
| Liver metastasis | |||
| Yes | 37 | 321.76 | 0.033 |
| No | 18 | 222.24 | |
| Tissue KRAS | |||
| Mutant | 25 | 248.43 | 0.589 |
| Wild type | 30 | 292.0 | |
| CA 19-9 | |||
| ≤37 IU/mL | 36 | 240.45 | 0.037 |
| >37 IU/mL | 19 | 351.76 | |
Abbreviation: CXCR4, C-X-C chemokine receptor type 4.