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. 2016 Jun 1;9:3307–3312. doi: 10.2147/OTT.S104511

Table 3.

Prognostic factors for OS in univariate analysis (N=55)

Variables Median OS (months) 95% CI P-value
Sex
 Male 17.03 12.71–21.353 0.529
 Female 19.53 9.45–29.61
Age (years)
 ≤65 18.37 14.81–21.93 0.365
 >65 23.93 13.24–34.62
Disease status
 Metastatic 20.33 15.98–24.68 0.728
 Recurrent 17.03 15.37–18.69
Primary site
 Colon 20.33 16.37–18.10 0.585
 Rectum 16.20 14.30–23.23
No of metastatic sites
 0–1 18.37 2.33–34.41 0.322
 ≥2 19.53 15.05–24.01
Liver metastasis
 Yes 18.37 14.88–21.86 0.033
 No 29.63 20.58–38.68
Palliative surgery
 Yes 23.93 15.93–31.93 0.036
 No 16.20 11.79–20.61
CA 19-9
 ≤37 IU/mL 20.90 12.01–29.79 0.120
 >37 IU/mL 17.40 9.91–24.89
Tissue KRAS
 Mutant 18.37 14.40–22.34 0.281
 Wild type 20.90 11.51–30.29
CXCR4
 ≤240.45 pg/mL 26.50 17.37–35.63 0.046
 >240.45 pg/mL 17.03 14.67–19.39

Abbreviations: CI, confidence interval; CXCR4, C-X-C chemokine receptor type 4; OS, overall survival.