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. Author manuscript; available in PMC: 2016 Jun 8.
Published in final edited form as: Mol Microbiol. 2015 Dec 22;99(6):999–1014. doi: 10.1111/mmi.13280

Fig. 10.

Fig. 10

The anti-malarial compound MMV007285 inhibits growth of yeast strains dependent upon PfPSD enzyme activity.

A. Heat-map representation of the results of the chemical screen using yeast as a model system.

B. Enlarged section of (A) with the list of 18 compounds that show enhanced PfPSD inhibitory activity in the absence, but not in the presence of ethanolamine.

C. Percentage growth of yeast cells harboring PkPSD in the absence (black bars) or presence of 100 μM (gray bars) of the compounds.