Table 2.
Mean contact times (seconds) during the test phase with novel and familiar objects for Tc1, Tg2576 and WT control mice.
Genotype | Mean contact times during the test stage (seconds) | |||
---|---|---|---|---|
Experiment 1a: Novel object recognition – 10 min vs 24 h delay | ||||
Novel object (10 min) | Novel object (24 h) | Familiar object (10 min) | Familiar object (24 h) | |
Tc1 | 5.692 | 7.132 | 4.048 | 2.956 |
WT | 6.399 | 7.716 | 2.120 | 2.791 |
Experiment 1b: Novel object recognition – 10 min vs immediate delay | ||||
Novel object (10 min) | Novel object (Immediate) | Familiar object (10 min) | Familiar object (Immediate) | |
Tc1 | 10.910 | 16.863 | 8.647 | 4.083 |
WT | 12.963 | 11.790 | 5.190 | 3.724 |
Experiment 2a: Object in place – 24 h versus immediate delay | ||||
Novel place (24 h) | Novel place (Immediate) | Familiar place (24 h) | Familiar place (Immediate) | |
Tc1 | 9.323 | 9.909 | 3.369 | 3.959 |
WT | 12.422 | 7.191 | 5.378 | 3.215 |
Experiment 2b: Object location – 10 min | ||||
Novel location (10 min) | Familiar location (10 min) | |||
Tc1 | 13.060 | 5.894 | ||
WT | 19.729 | 4.616 | ||
Experiment 3: Novel odour recognition – 10 min vs 24 h delay | ||||
Novel odour (10 min) | Novel odour (24 h) | Familiar odour (10 min) | Familiar odour (24 h) | |
Tc1 | 8.819 | 7.413 | 7.580 | 3.640 |
WT | 7.493 | 7.209 | 2.821 | 3.240 |
Experiment 4: Yoked novel object recognition | ||||
Novel object (10 min) | Novel object (24 h) | Familiar object (10 min) | Familiar object (24 h) | |
Tg2576 | 4.774 | 1.759 | 1.924 | 1.767 |
WT | 10.543 | 13.698 | 4.499 | 6.244 |