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. 2016 Feb 25;26(11):4098–4106. doi: 10.1007/s00330-016-4253-2

Table 2.

Summary of maximum standardised uptake value (SUVmax), signal-to-noise (SNR), signal-to-background (SBR) and percentage difference in SUVmax across the entire cohort and classified according to histopathology

All (n=112) Positive (n=25) Negative (n=87)
OSEM BPL OSEM BPL OSEM BPL
SUVmax
 Mean 3.2 4.0 5.2 7.0 2.6 3.1
 Median 2.4 2.9 3.4 4.4 2.3 2.8
 Range 1.0 – 17.0 1.0 – 25.3 1.3 – 17.0 1.3 – 25.3 1.0 – 6.9 1.0 – 8.3
 Wilcoxon p value <0.0001 <0.0001 <0.0001
SNR
 Mean 27.7 40.9 43.4 73.7 23.2 31.5
 Median 21.2 27.4 36.0 38.4 20.7 25.8
 Range 6.0 – 131.0 5.2 – 281.4 9.1 – 131.0 16.1 – 281.4 6.0 – 67.5 5.2 – 106.5
 Wilcoxon p value <0.0001 <0.0001 <0.0001
SBR
 Mean 2.2 2.6 3.6 4.5 1.8 2.0
 Median 1.8 1.9 2.9 3.0 1.7 1.9
 Range 0.6 – 10.2 0.6 – 18.1 0.8 – 10.2 0.8 – 18.1 0.6 – 4.1 0.6 – 5.4
 Wilcoxon p value <0.0001 <0.001 <0.0001
%ΔSUVmax
 Mean 16.4 % 23.7 % 14.3%
 Median 14.6 % 24.2 % 13.4%
 Range -11.8 – 87.0 % -3.0 – 87.0 % -11.8 – 48.4%
 Spearman p value (correlation vs size) 0.0001 <0.0001 0.125
 Mann-Whitney U p value - 0.032

BPL Bayesian penalised likelihood reconstruction, OSEM ordered subset expectation maximum