Table 1.
Demographic and clinical phenotypes of the studied participants
| Patients | Controls | ||
|---|---|---|---|
| Parameters | n=545 | n=400 | p Value |
| Gender | |||
| Male | 501 (92%) | 368 (92%) | |
| Female | 44 (08%) | 32 (08%) | |
| Clinical characteristics | |||
| Age, year | 51.6±10.9 | 50.0±9.7 | NS |
| BMI, kg/m2 | 24.3±4.1 | 23.7±4.3 | 0.047 |
| SBP, mm Hg | 160.2±19.3 | 115.9±9.4 | <0.0001 |
| DBP, mm Hg | 97.2±9.6 | 76.4±6.6 | <0.0001 |
| MAP, mm Hg | 117.6±13.7 | 90.5±6.9 | <0.0001 |
| Alcohol consumption | 55 (10%) | 24 (06%) | 0.030 |
| Smoking history | 66 (12%) | 36 (09%) | 0.150 |
| Family history of hypertension | 425 (78%) | (00) 00% | <0.0001 |
| Biochemical parameters | |||
| ACE, U/L | 106.3±32.7 | 86.0±31.2 | <0.0001 |
| Total cholesterol, mmol/L | 3.3±1.2 | 2.6±1.3 | <0.0001 |
| Triglyceride, mmol/L | 1.3±0.8 | 1.0±0.6 | <0.0001 |
| Uric acid, mg/dL | 4.8±1.5 | 4.7±1.5 | NS |
| Glucose, mg/dL | 101.0±23.0 | 99.2±26 | NS |
| Serum creatinine, mg/dL | 1.15±0.45 | 1.14±0.44 | NS |
Data are presented as mean±SD. p Values were calculated using EPIINFO v.6 (Center for Disease Control, Atlanta, Georgia, USA) software. A value of p<0.05 was considered statistically significant.
ACE, angiotensin converting enzyme; BMI, body mass index; DBP, diastolic blood pressure; MAP, mean arterial pressure; n, number of participants; NS, non-significant; SBP, systolic blood pressure.