Table 2. Summary of results from the protein microarray for all 16 SNPs examined.
| Protein | N | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PKNOX2 | 5 | R | R | B | R | NR | R | R | |||||||||
| PRNP | 3 | NR | NR | R | NR | ||||||||||||
| EIF1AD | 1 | R | B | R | |||||||||||||
| GADD45A | 6 | NR | B | B | |||||||||||||
| ZKSCAN5 | 2 | NR | R | R |
Proteins listed bind at least 3 of the 16 SNPs tagged by rs1006737, none of the 3 control oligos, and 6 or less of the 460 DNA motifs previously tested [29,30]. Number of DNA motifs previously bound is shown in the second column labeled N. “NR” indicates protein binds only to the non-risk allele, “R” indicates the protein binds only the risk allele, “B” indicates protein binds both alleles, blank cells indicate no binding. SNPs are in columns 3 through 18 labeled as in Table 1.