Table 1. Effects of chronic methamphetamine administration on regional rat brain volume.
| Vehicle | 4 mg/kg MA | 8 mg/kg MA | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Striatum | 87.2 | ± | 3.6 | 99.6 | ± | 2.7 | 100.6 | ± | 3.9 * |
| Globus pallidus | 11.9 | ± | 1.1 | 12.7 | ± | 1.3 | 11.8 | ± | 0.6 |
| Cerebral cortex | 748.7 | ± | 9.5 | 803 | ± | 11.4 | 763.4 | ± | 17.2 |
| Hippocampus | 117.3 | ± | 2.9 | 126.2 | ± | 3.6 | 116.5 | ± | 4.1 |
| Cerebellum | 324.3 | ± | 7.9 | 362.1 | ± | 17.9 | 348 | ± | 9.5 |
| External capsule | 107.8 | ± | 4.9 | 110 | ± | 3.7 | 107.9 | ± | 3.3 |
| Total brain | 2592.4 | ± | 39 | 2708.7 | ± | 95.2 | 2633.9 | ± | 43.1 |
The numbers represent mean ± SEM, expressed in mm3.
* denotes significant difference from vehicle, p<0.05.