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. 2016 Jun 8;11(6):e0156705. doi: 10.1371/journal.pone.0156705

Table 3. The most cost-effective strategies (CES) based on different calculation methods.

The cost-effectiveness of 11 strategies were estimated with different methods. Effectiveness was measured with QALY, LYG, and undiscounted QALY.

Calculation methods of cost-effectiveness First CES Second CES Third CES Sensitive to base case
Base Case HPV 35–10 Pap smear 35–10 HPV 35–5 -
Life years gained (LYG) Pap smear 35–10 Pap smear 35–5 Pap smear 30–5 Sensitive
Undiscounted QALY HPV 35–10 HPV 35–5 Pap-smear 35–10 Sensitive
One-way sensitivity analysis of decreasing sensitivity of HPV DNA Pap smear 35–10 Pap smear 35–5 Pap-smear 30–5 Sensitive
One-way sensitivity analysis of decreasing sensitivity of Pap smear HPV 35–10 HPV 35–5 HPV 30–5 Sensitive
One-way sensitivity analysis of decreasing specificity of HPV DNA Pap smear 35–10 HPV 35–10 Pap 35–5 Sensitive
One-way sensitivity analysis of decreasing specificity of Pap smear HPV 35–10 Pap smear 35–10 HPV 30–10 Sensitive
One-way sensitivity analysis of increasing sensitivity of HPV DNA HPV 35–10 HPV 35–5 HPV 30–10 Sensitive
One-way sensitivity analysis of increasing specificity of HPV DNA HPV 35–10 Pap smear 35–10 HPV 35–5 Not sensitive
One-way sensitivity analysis of increasing specificity of Pap smear Pap smear 35–10 Pap smear 35–5 Pap smear 30–5 Sensitive
One-way sensitivity analysis based on increasing the cost of HPV DNA Pap smear 35–10 Pap smear 35–5 Pap smear 30–5 Sensitive
One-way sensitivity analysis based on increasing the cost of Pap smear HPV 35–10 HPV 35–5 HPV 30–10 Sensitive