Fig. 4.—

Difference between the estimation of the genomic distance and the inversion distance (y-axis), for statistical estimators with different parameters (number of solid regions and breakage probabilities) (x-axis). The points represent 21 pairwise amniote genome comparisons. Distance estimates are obtained from (ER1—pseudouniform), if solid regions are genes and intergene breakage probabilities p_is are all equal; (ER1—uniform), if solid regions are genes and p_is proportional to intergene sizes; (ER2), with a parameterized number $\tilde{n}$ of fragile regions, and breakage probabilities distributed in fragile regions according to a flat Dirichlet law. The difference should be nonnegative if the scenario is likely, given the parameters $\tilde{n}$ and $p_i$.