Table 3 . Study Characteristics .

Study	Number of Participants	Blinding	Design	Follow up	Baseline Severity ADHD-RS Total Score	Mean Daily Dose of Amoxetine and Frequency	Mean Daily Dose Methylphenidate and Frequency
Spencer et al. 2002	163	Double Blind	Parallel group	9 weeks	Atomoxetine= 39.5	1.56mg/kg Twice a day	IR MPH= 1.12mg/kg Twice a day
Kratochvil et al. 2002	228	Open Label	Parallel group	10 weeks	Atomoxetine= 39.4 MPH= 37.6	0.48mg/kg or 1.4mg/kg/kg Twice daily	Final mean dose 0.85mg/kg Three times a day
Sangal et al. 2005	85	Double Blind	Cross over	7 weeks	Atomoxetine= 39.6 MPH not stated	1.56mg/kg/day Twice a day IR MPH=	1.12mg/kg Three times a day
Kemner et al. 2005	1323	Open Label	Parallel group	3 weeks	Atomoxetine= 38.6 (SD 8.1) MPH= 39	1.08mg/kg/Once a day	OROS-MPH 1.01mg/kg/day (IR equivalent 0.841mg/kg) Once a day
Wang et al. 2007	330	Double Blind	Parallel group	8 weeks	Atomoxetine= 38.6 (SD 7.6) MPH= 37.4 (SD 7.6	Final range 0.8mg/kg-1.8 mg/kg Once a day	IR MPH= 17.8/mg/day Twice a day
Prasad et al. 2007	180	Open Label	Parallel group	10 weeks	Atomoxetine= 45.5 (SD 8.7) MPH not stated	1.5mg/kg Once a daily 8pts got twice daily	IR MPH= 0.8mg/kg OROS-MPH= 1.03mg/kg (IR equivalent= 0.858mg/kg)
Newcorn et al. 2008	442	Double Blind	Parallel group	6 weeks	Atomoxetine= 40.9 (SD 8.8) MPH= 40 (SD 8.8)	1.45mg/kg Twice a day	OROS-MPH= 1.16mg/kg (IR equivalent= 0.966mg/kg Once a day
Yildiz et al. 2010	25	Open Label	Parallel group	12 weeks	Parents TDSM- IV inattention scores atomoxetine= 16.72 MPH= 17.72	1.28mg/kg/day Once a day	OROS-MPH= 1.07mg/kg (IR= equivalent 0.89mg/kg) Once a day
Bedard et al. 2014	102	Double Blind	Cross over	4-6 weeks	Atx= 36.5±11.09 MPH= 37.9±10.96	1.4±0.5 mg/kg/day	OROS-MPH= 52.4±16.6mg
Garg et al. 2014	69	Open label	Parallel group	8 weeks	Atx= 55.03 (14.44) MPH= 51.18 (0.86)	17.46 (7.22) mg/day (or 0.7mg/kg/day) Once a day	IR MPH=17.35 (7.52) mg/ day (or 0.62mg/kg/day) Once or Twice a day