Table 1 . Components of structured question .

● Population: Patients with advanced prostate cancer‏; ● Intervention: ADT using degarelix‏; ● Comparator: ADT usingGnRH agonists (includinggoserelin, leuprolinandtriptorelin) with or without anti-androgen therapy‏; ● Outcome: reducing prostate volume, health related quality of life, IPSS score, general survival, reducing testosterone level, reducing PSA level, drug induced side effects‏; ● Type of studies: Randomized Controlled Trials relevant to our PICO‏;