Table 4 . Proportion of Patients with Improvement or Deterioration in EDSS .

Study	IVIG	Placebo	OR (95%CI)	% Weight
	Improved
Fazekas (1997)	0.31	0.14	2.787 (1.217-6.379)	42.20
Achiron (1998)	0.24	0.11	3.000 (0.507-17.740)	9.43
Strasser (2000)	0.34	0.14	3.343 (1.473-5.585)	46.65
Koçer (2004) M-H pooled OR	0.25	0.083	3.667 (0.323-41.590)	4.72
	Deteriorated					3.080 (1.769-5.282)
Fazekas et al. (1997)	0.16	0.23	0.627 (0.276-1.427)	30.31
Achiron et al. (1998)	0.14	0.17	0.706 (0.136-3.658)	7.12
Strasser et al.(2000)	0.18	0.23	0.756 (0.333-0.857)	29.35
Lewanska et al. (2002) 0.2g/kg	0.24	0.47	0.346 (0.080-1.507)	12.81
Lewanska et al. (2002) 0.4g/kg	0.07	0.47	0.080 (0.009-0.756)	14.66
Kocer (2004)	0.08	0.25	0.273 (0.024-3.093)	5.76
M-H pooledOR			0.534 (0.333-0.857)

IVIG= Intravenous immunoglobulin; EDSS=Expanded Disability Status Scale; OR= odds ratio