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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Am J Med Genet A. 2015 Dec 10;170(4):825–837. doi: 10.1002/ajmg.a.37495

TABLE I.

Characteristics of Live Born Infants With Trisomy 13 and Trisomy 18 in Nine US States, 1999–2007 Birth Cohort

Characteristic Trisomy 13
Trisomy 18
Number births Percent Number births Percent
Infant sex
 Male 347 50.1 427 38.4
 Female 340 49.1 681 61.2
 Unknown 6 0.9 5 0.4
Gestational age
 <32 weeks 122 17.6 206 18.5
 32–36 weeks 223 32.2 277 24.9
 ≥37 weeks 336 48.5 605 54.4
 Unknown 12 1.7 25 2.2
Plurality
 Single 675 97.4 1,065 95.7
 Multiple 15 2.2 41 3.7
 Unknown 3 0.4 7 0.6
Maternal race/ethnicity
 Non-Hispanic White 327 47.2 471 42.3
 Non-Hispanic Black 110 15.9 208 18.7
 Hispanic 217 31.3 366 32.9
 Non-Hispanic Asian/PI 21 3.0 38 3.4
 Other/unknown 18 2.6 30 2.7
Maternal age
 <19 years 53 7.6 67 6.0
 20–24 years 126 18.2 156 14.0
 25–29 years 149 21.5 179 16.1
 30–34 years 155 22.4 200 18.0
 ≥35 years 210 30.3 511 45.9
Geographic area
 Metropolitan 618 89.2 991 89.0
 Non-metropolitan 72 10.4 117 10.5
 Unknown 3 0.4 5 0.4
State
 Arizona 68 9.8 118 10.6
 Colorado 52 7.5 59 5.3
 Georgia 32 4.6 61 5.5
 Illinois 63 9.1 127 11.4
 Massachusetts 37 5.3 49 4.4
 North Carolina 50 7.2 92 8.3
 New Jersey 50 7.2 76 6.8
 New York 85 12.3 127 11.4
 Texas 256 36.9 404 36.3
Presence of heart defectsa
 With heart defects 117 16.9 193 17.3
 No heart defects 576 83.1 920 82.7
Presence of omphalocele
 With omphalocele 52 7.5 58 5.2
 No omphalocele 641 92.5 1,055 94.8
Birth period
 1999–2002 264 38.1 400 35.9
 2003–2007 429 61.9 713 64.1
Total 693 100.0 1,113 100.0
a

Heart defects include common truncus, transposition of great arteries, tetralogy of Fallot, atrioventricular septal defect, aortic valve stenosis, hypoplastic left heart syndrome, and coarctation of aorta.

PI, Pacific Islander.