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. 2016 Apr 27;2:16012. doi: 10.1038/npjschz.2016.12

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Copyright © 2016 Schizophrenia International Research Society/Nature Publishing Group

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Gene–drug interactome. The network shows the drugs that target genes from the schizophrenia interactome. Drugs are shown as round nodes colored in green and genes as square nodes colored in dark blue (schizophrenia genes), light blue (known interactors), and red (novel interactors). Nervous system drugs (based on Anatomic category of ATC classification) are shown as larger size green colored nodes compared with other drugs. Drugs that are in clinical trials for schizophrenia are labeled purple. ATC, anatomic, therapeutic and chemical classification.