Table 2.

“Cell-Adhesion–Related” Genes Identified in Multiple Genomewide Association Studies of Addiction and Related Disorders^a

Gene	Description	Chr	bp	P-value
BAI3	Brain-specific angiogenesis inhibitor 3	6	69404158	<0.00001
CDH13	Cadherin 13	16	81218079	<0.00001
CLSTN2	Calsyntenin 2	3	141136897	<0.00001
CNTNAP2	Contactin-associated protein-like 2	7	145444386	<0.00001
CSMD1	CUB and Sushi multiple domains 1	8	2782789	<0.00001
CTNNA2	Catenin α 2	2	79593634	<0.00001
DAB1	Disabled homolog 1	1	57236167	<0.00001
DSCAM	Down syndrome cell-adhesion molecule	21	40306213	<0.00001
NRXN1	Neurexin 1	2	50000992	<0.00001
PTPRD	Receptor protein tyrosine phosphatase D	9	8307268	<0.00001
SGCZ	Sarcoglycan zeta	8	13991744	<0.00001
ASTN2	Astrotactin 2	9	118227328	0.000070
CNTN4	Contactin 4	3	2117247	0.000110
CNTN6	Contactin 6	3	1109629	0.000120
LRP1B	Low-density lipoprotein-related protein 1B	2	140705466	0.000150
NRG1	Neuregulin 1	8	32525295	0.000240
ITGB8	Integrin β 8	7	20337250	0.000260
PTPRM	Receptor protein tyrosine phosphatase M	18	7557817	0.000290
ROR1	Receptor tyrosine kinase-like orphan rec 1	1	64012302	0.000290
TRIO	Triple functional domain/PTPRF interact	5	14196829	0.000690
CSMD2	CUB and Sushi multiple domains 2	1	33752196	0.000830
CNTN5	Contactin 5	11	98397081	0.000980
CTNNA3	Catenin α 3	10	67349937	0.001090
LRRN6C	Leucine-rich repeat neuronal 6C	9	27938528	0.001340
CTNND2	Catenin δ 2	5	11024952	0.003270
ANKS1B	Ankyrin repeat sterile α domain 1B	12	97653202	0.003410
SEMA3C	Semaphorin 3C	7	80209790	0.006310

Columns list gene symbol, gene description, chromosome, base pair of gene start, and overall P-value for this gene in this entire dataset (described in Uhl et al., 2008a), based on 100,000 Monte Carlo simulation trials.

^aModified from Uhl et al., 2008a.