Table 2.
Impact of marital status on diagnosis and treatment of gastric cancer
| Variables | Metastatic disease at Dx | Surgery performed or not 2 | ||
|---|---|---|---|---|
| OR1 (95% CI) | P | OR2 (95% CI) | P | |
| Sex | NI | NI | ||
| Male vs. Female | ||||
| Age 1 | 0.983 (0.981–0.985) | <0.001 | 0.962 (0.958–0.966) | <0.001 |
| Race/ethnicity | ||||
| White (non‐Hispanic) | Reference | Reference | ||
| Black | 0.825 (0.748–0.911) | <0.001 | 0.769 (0.657–0.899) | 0.001 |
| Hispanic | 1.040 (0.954–1.134) | 0.368 | 0.903 (0.781–1.044) | 0.167 |
| Othera | 0.681 (0.620–0.747) | <0.001 | 1.469 (1.257–1.716) | <0.001 |
| Year of diagnosis | ||||
| 2004–2005 | Reference | Reference | ||
| 2006–2007 | 1.045 (0.964–1.131) | 0.286 | 1.026 (0.900–1.169) | 0.700 |
| 2008–2009 | 0.973 (0.898–1.054) | 0.554 | 0.850 (0.749–0.965) | 0.012 |
| 2010 | 1.089 (0.988–1.200) | 0.080 | 0.747 (0.641–0.871) | <0.001 |
| Tumor location | ||||
| Noncardia | Reference | Reference | ||
| Cardia | 0.716 (0.667–0.769) | <0.001 | 0.441 (0.395–0.493) | <0.001 |
| Differentiated grade | ||||
| Well/moderateb | Reference | Reference | ||
| Poor/unc | 1.428 (1.322–1.543) | <0.001 | 1.044 (0.932–1.170) | 0.457 |
| Unknown | 3.403 (3.066–3.777) | <0.001 | 0.197 (0.166–0.234) | <0.001 |
| Histological type | ||||
| Adenocarcinoma | Reference | Reference | ||
| Mucinous cell adenocarcinoma | 0.621 (0.502–0.768) | <0.001 | 2.627 (1.813–3.806) | <0.001 |
| ignet ring cell carcinoma | 0.775 (0.720–0.835) | <0.001 | 0.996 (0.880–1.127) | 0.996 |
| Marital status | ||||
| Married | Reference | Reference | ||
| Single (never married) | 1.138 (1.040–1.245) | 0.005 | 0.559 (0.482–0.647) | <0.001 |
| Divorced/separated | 1.080 (0.972–1.199) | 0.064 | 0.681 (0.576–0.806) | <0.001 |
| Widowed | 1.086 (0.989–1.192) | 0.085 | 0.571 (0.499–0.653) | <0.001 |
OR1 adjusted for demographics (age and race), tumor location, differentiated grade, histological type, and year of diagnosis. OR2 adjusted for demographics (age and race), tumor location, differentiated grade, histological type, and year of diagnosis. NI: not included in the bivariate logistic regression analysis. HR, hazard ratio; OR, odds ratio; CI, confidence interval.
1Age was analyzed as continuous measurements in both analyses.
2Exclude patients with metastatic disease. The event for modeling surgery performed or not is “surgery performed”.
Include American Indian/AK Native, Asian/Pacific Islander, and unknown.
Highly / moderately differentiated.
Poorly differentiated / undifferentiated.