Table 3.
Impact of marital status on CSS of gastric cancer
| Variables | CSS | |
|---|---|---|
| HR3 (95% CI) | P | |
| Sex | ||
| Male | Reference | |
| Female | 0.956 (0.920–0.992) | 0.018 |
| Age* | 1.018 (1.017–1.020) | <0.001 |
| Race | ||
| White | Reference | |
| Black | 1.049 (0.994–1.107) | 0.079 |
| Hispanic | 0.969 (0.924–1.017) | 0.205 |
| Other | 0.773 (0.733–0.816) | <0.001 |
| Year of diagnosis | ||
| 2004–2005 | Reference | |
| 2006–2007 | 0.913 (0.874–0.953) | <0.001 |
| 2008–2009 | 0.871 (0.833–0.910) | <0.001 |
| 2010 | 0.876 (0.828–0.926) | <0.001 |
| Tumor location | ||
| Noncardia | Reference | |
| Cardia | 1.007 (0.968–1.048) | 0.728 |
| Differentiated grade | ||
| Well/moderate b | Reference | |
| Poor/un c | 1.225 (1.172–1.281) | <0.001 |
| Unknown | 1.420 (1.341–1.503) | <0.001 |
| Histological type | ||
| Adenocarcinoma | Reference | |
| Mucinous cell adenocarcinoma | 0.825 (0.734–0.928) | 0.001 |
| Signet ring cell carcinoma | 1.053 (1.012–1.097) | 0.012 |
| Stage | ||
| I | Reference | |
| II | 1.513 (1.412–1.621) | <0.001 |
| III | 2.272 (2.130–2.424) | <0.001 |
| IV | 5.445 (5.171–5.734) | <0.001 |
| Marital status | ||
| Married | Reference | |
| Single (never married) | 1.279 (1.216–1.344) | <0.001 |
| Divorced/separated | 1.217 (1.149–1.290) | <0.001 |
| Widowed | 1.274 (1.209–1.342) | <0.001 |
HR3 adjusted for demographics (age, sex, and race), tumor location, histological type, differentiated grade, stage, and year of diagnosis. CSS, cause‐specific survival; CI, confidence interval; HR, hazard ratio.
*Age was analyzed as continuous measurement.
bHighly / moderately differentiated.
cPoorly differentiated / undifferentiated.