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. 2016 May 31;38(1):3–15. doi: 10.3892/ijmm.2016.2620

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Copyright: © Katoh et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Genome-based precision medicine for cancer patients. Amp, amplification; Fus, fusion; Mut, mutation. Patients with breast cancer (red), gastric cancer (green), lung cancer (blue) and other cancers (yellow) are reorganized into the groups of cancer patients with specific genetic alterations. Patients with fibroblast growth factor receptor (FGFR), EGFR, HER2, ALK and RET alterations are prescribed FGFR inhibitor, EGFR inhibitor, HER2 monoclonal antibody (mAb), ALK inhibitor and RET inhibitor, respectively. However, at present, there is no targeted therapy for cancer patients with MYC Amp, RHOA Mut, TP53 Mut, ASXL1 Mut, etc.