Table 1.
Performance on Neuropsychological Tests
| Male Comparison Subjects | Female Comparison Subjects | Male METH Subjects | Female METH Subjects | METH Effect | Sex Effect | METH × Sex Interaction | |
|---|---|---|---|---|---|---|---|
| Age (years) | 30.9 ± 7.8 | 30.0 ± 9.2 | 33.1 ± 7.8 | 30.9 ± 6.4 | ns | ns | ns |
| Education (years) | 14.4 ± 1.0 | 14.2 ± 1.1 | 12.8 ± 1.5 | 12.3 ± 1.4 | F = 27.8; p < .0001 | ns | ns |
| Estimated Verbal IQ | 100.14 ± 11.29 | 102.67 ± 11.50 | 101.11 ± 12.08 | 100.18 ± 11.22 | ns | ns | ns |
| Motor and Psychomotor Tasks | |||||||
| Time gait (s) | 9.94 ± 1.45 | 10.15 ± 1.67 | 10.11 ± 1.51 | 10.41 ± 1.21 | ns | ns | ns |
| Pegboard (dominant) (s) | 62.0 ± 5.47 | 59.08 ± 8.10 | 68.10 ± 12.06 | 62.90 ± 15.22 | ns | ns | ns |
| Pegboard (non-dominant) (s) | 77.4 ± 19.07 | 66.92 ± 11.29 | 75.95 ± 13.20 | 76.8 ± 16.1 | ns | F = 6.1; p = .02 | ns |
| Trail making A (s) | 23.91 ± 3.94 | 22.83 ± 6.48 | 26.43 ± 6.13 | 24.96 ± 10.79 | ns | ns | ns |
| Trail making B (s) | 59.82 ± 19.51 | 54.67 ± 20.69 | 71.33 ± 22.69 | 55.04 ± 19.05 | ns | ns | ns |
| Symbol digit modalities | 55.18 ± 8.02 | 61.75 ± 10.45 | 48.33 ± 7.74 | 52.00 ± 8.02 | ns | ns | ns |
| Memory and Learning - Auditory Verbal Learning Test | |||||||
| Immediate recall (s) | 6.27 ± 1.90 | 7.17 ± 2.04 | 5.57 ± 1.08 | 6.91 ± 1.91 | ns | ns | ns |
| After 5 trials (s) | 12.73 ± 1.62 | 13.25 ± 1.96 | 11.38 ± 2.33 | 13.13 ± 2.03 | ns | ns | F =5.2; p =.03 |
| With interference (s) | 11.09 ± 3.05 | 11.75 ± 2.96 | 9.57 ± 2.77 | 11.65 ± 2.01 | ns | ns | F = 8.2; p = .006 |
| Delayed recall (s) | 11.27 ± 2.10 | 11.58 ± 2.07 | 9.29 ± 2.92 | 11.61 ± 2.25 | ns | ns | F = 4.9; p = .03 |
| Executive Function-Stroop Color Interference Tests and Verbal Fluency | |||||||
| Stroop color (s) | 60.82 ± 9.25 | 57.08 ± 10.55 | 63.60 ± 10.32 | 61.65 ± 12.07 | ns | ns | ns |
| Stroop words (s) | 46.82 ± 9.64 | 41.83 ± 6.71 | 48.19 ± 8.27 | 47.39 ± 9.81 | ns | ns | ns |
| Stroop interference (s) | 116.36 ± 23.01 | 101.83 ± 22.65 | 123.80 ± 25.92 | 118.44 ± 25.06 | ns | ns | ns |
| Verbal fluency (# correct) | 40.3 ± 11.98 | 37.4 ± 12.5 | 37.5 ± 7.7 | 39.5 ± 13.97 | F = 4.1; p = .05 | ns | ns |
| Visual Construction and Visual Memory - Rey-Osterrieth Complex Figure Test | |||||||
| Copy | 29.7 ± 5.06 | 30.8 ± 3.97 | 30.3 ± 2.73 | 30.1 ± 3.48 | ns | ns | ns |
| Immediate recall | 14.9 ± 8.58 | 16.4 ± 4.18 | 16.3 ± 4.9 | 17.8 ± 7.3 | ns | ns | ns |
| Delayed recall | 18.3 ± 4.54 | 17.2 ± 6.76 | 15.8 ± 5.66 | 17.1 ± 4.51 | ns | ns | ns |
None of the group differences for neuropsychological tests are significant after Bonferroni correction. Results are presented as mean ± standard deviation; analysis of covariance (ANCOVA): F (1, 63).
METH, methamphetamine.