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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Bone. 2016 Apr 12;88:39–46. doi: 10.1016/j.bone.2016.04.003

Table 3.

HR-pQCT, ITS, cortical, and mechanical parameters at distal radius in vertebral fracture subjects and controls

Variables Vertebral Fracture (Mean ± SEM) Control (Mean ± SEM) p-Value OR (95% CI) AUC
HR-pQCT
<0.001b
 vBMD (mg HA/cm3) 250 ± 8 304 ± 10 1.35 (1.09, 1.61) 0.73
 Tb.BMD (mg HA/cm3) 107 ± 5 140 ± 6 <0.001c 1.45 (1.13, 1.77) 0.74
 Ct.BMD (mg HA/cm3) 812 ± 12 852 ± 10 <0.001 1.11 (0.95, 1.68) 0.63
 BV/TV 0.090 ± 0.005 0.116 ± 0.005 <0.001b 1.39 (1.10, 1.68) 0.73
 Tb.N (1/mm) 1.587 ± 0.055 1.832 ± 0.049 0.001a 1.26 (1.02, 1.49) 0.69
 Tb.Th (mm) 0.056 ± 0.002 0.063 ± 0.001 0.002a 1.18 (0.99, 1.36) 0.71
 Tb.Sp (mm) 0.613 ± 0.029 0.502 ± 0.017 0.001a 1.81 (0.89, 2.73) 0.69
ITS
 pBV/TV 0.082 ± 0.005 0.103 ± 0.005 0.002a 1.11 (0.98, 1.25) 0.69
 rBV/TV 0.137 ± 0.005 0.154 ± 0.004 0.007 1.13 (0.97, 1.29) 0.66
 aBV/TV 0.089 ± 0.004 0.108 ± 0.004 0.002a 1.17 (1.00, 1.34) 0.70
 P-R ratio 0.611 ± 0.040 0.684 ± 0.038 0.12 0.96 (0.91, 1.01) 0.62
 pTb.N (1/mm) 1.224 ± 0.022 1.344 ± 0.021 <0.001b,* 1.34 (1.09, 1.58) 0.73
 rTb.N (1/mm) 1.765 ± 0.023 1.862 ± 0.021 0.003 1.21 (1.00, 1.41) 0.69
 pTb.Th (mm) 0.222 ± 0.002 0.220 ± 0.001 0.14 0.99 (0.91, 1.06) 0.56
 rTb.Th (mm) 0.208 ± 0.001 0.209 ± 0.001 0.46 0.94 (0.92, 0.95) 0.55
 pTb.S (mm2) 0.191 ± 0.002 0.186 ± 0.001 0.04 1.07 (0.93, 1.21) 0.63
 rTb.ℓ (mm) 0.660 ± 0.005 0.633 ± 0.004 <0.001b,* 1.48 (1.11, 1.85) 0.74
 P-P Junc.D (1/mm3) 1.344 ± 0.074 1.786 ± 0.083 <0.001b 1.29 (1.08, 1.50) 0.74
 P-R Junc.D (1/mm3) 2.830 ± 0.139 3.705 ± 0.157 <0.001b,* 1.35 (1.11, 1.59) 0.74
 R-R Junc.D (1/mm3) 2.595 ± 0.111 3.021 ± 0.108 0.007 1.12 (0.97, 1.27) 0.67
Cortical
 Tt.Ar (mm2) 244 ± 6 230 ± 5 0.05 1.04 (0.92, 1.16) 0.62
 Tb.Ar (mm2) 203 ± 6 182 ± 5 0.02 1.21 (0.97, 1.44) 0.65
 Ct. Ar (mm2) 47 ± 1 51 ± 1 0.02 1.08 (0.97, 1.20) 0.63
 Ct.Th (mm) 0.783 ± 0.024 0.889 ± 0.026 0.003 1.18 (1.00, 1.36) 0.70
 Ct.Po 0.055 ± 0.004 0.047 ± 0.003 0.11 1.02 (0.94, 1.11) 0.60
 Ct.Po.Dm (mm) 0.154 ± 0.003 0.150 ± 0.003 0.16 0.99 (0.93, 1.04) 0.58
FEA
 Whole bone stiffness (N/mm) 68,158 ± 2,495 82,642 ± 2,883 <0.001b 1.45 (1.23, 1.66) 0.71
 Trabecular bone stiffness (N/mm) 14,551 ±1,586 18,601 ± 1,402 0.06 0.99 (0.92, 1.07) 0.65
 Whole bone estimated failure load (N) 4,397 ± 124 5031 ± 143 0.001a 1.15 (0.98, 1.32) 0.69
 Trabecular bone estimated failure load (N) 942 ± 81 1,126 ± 68 0.08 1.00 (0.93, 1.07) 0.61
a

p<0.05,

b

p<0.01,

c

p<0.001, group difference remains significant after adjusting for aBMD at ultradistal radius;

*

p<0.05, group difference remains significant after adjusting for vBMD at distal radius.