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. Author manuscript; available in PMC: 2016 Jun 9.
Published in final edited form as: Cell Rep. 2016 May 26;15(10):2136–2146. doi: 10.1016/j.celrep.2016.05.009

Figure 3. Antigen activated splenocytes from the EAE-CTRL and the EAE-FMD mice had similar encephalitogenic effects.

Figure 3

(n=5–6 / group; mean ± S.E.M, * p < 0.05, ** p<0.01; *** p < 0.001; t test, 1-way ANOVA & Bonferroni Post Test).

a. Diagram for the adoptive transfer EAE model.

b–d. Quantification of the (b) TNFα, (c) IFNγ, and (d)IL-17 (pg/mL) of the supernatant from ex-vivo culture of splenocytes from naïve, EAE CTRL, and EAE FMD either with or without MOG35-55 and IL-23 re-activation

e–f. Quantification of TH1 or TH17 (represented by % of CD4+) from lymphocytes culture of EAE CTRL and EAE FMD with or without MOG35-55 and IL-23 re-activation

g. Incidence rate of adoptive transfer EAE groups.

h. EAE severity score of adoptive transfer EAE groups.

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