Table 1.
Summary of Model Specific Constants
| Lower K2 Boundary1 |
Upper K2 Boundary |
|||||||
|---|---|---|---|---|---|---|---|---|
| WT | A8V | A8V | A8V | WT | A8V | A8V | A8V | |
| ΔK1 (note2) | 0.77 | 0.67 | 0.59 | 0.77 | 0.67 | 0.59 | ||
| K 0 ′ | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| 3 α | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 | 3.25 |
| n | 5 | 5 | 5 | 5 | 5 | 5 | 5 | 5 |
| K 1 | 275.00 | 211.54 | 183.33 | 161.76 | 1400.00 | 1076.92 | 933.33 | 823.53 |
| K2 (note3) | 1.67 | 1.67 | 1.67 | 1.67 | 10.00 | 10.00 | 10.00 | 10.00 |
| K3 (note4) | 27.55 | 21.19 | 18.37 | 16.21 | 14.00 | 10.77 | 9.33 | 8.24 |
| K4 | 0.17 | 0.17 | 0.17 | 0.17 | 0.10 | 0.10 | 0.10 | 0.10 |
| Range of Activation | ~10% to- 90% | ~10% to- 90% | ~10% to- 90% | ~10% to- 90% | ~5% to- 95% | ~5% to- 95% | ~5% to- 95% | ~5% to- 95% |
| Figures | 3A, 3C | 3A, 3C | 3A, 3C | 3A, 3C | 3B, 3D | 3B, 3D | 3B, 3D | 3B, 3D |
| Curve | Black | Red | Blue | Purple | Black | Red | Blue | Purple |
1
K2, K4, n, and α have values used previously (32). Values are dimensionless unless otherwise indicated.
2
Multiplier of WT K1
3
Multiple of 106 M−1
4
Not an adjustable parameter. Tabulated value calculated from K1K4/K2