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. Author manuscript; available in PMC: 2017 Jun 21.
Published in final edited form as: Analyst. 2016 Apr 7;141(12):3526–3539. doi: 10.1039/c6an00325g

Figure 7.

Figure 7

The surface coverage (known as Janus balance) of cell-targeting ligands on Janus particles can be used to control the cellular entry efficiency of the particles. (a) Fabrication of the patchy Janus particles using microcontact printing method and quantification of the ligand patch size using the arc angle θ. (b) The cellular internalization efficiency (% internalization) of 1.6-μm Janus particles (red solid triangles) increases with larger ligand patch size. For comparison, the % internalization of 1.6-μm Janus particles is lower than that of particles uniformly coated with the same number of ligands. Reprinted from ref 36 Copyright 2015 American Chemical Society.