Table I.

Body composition and food, water intake

	6 months		12 months		2-way ANOVA
Parameters	Control	IUGR	Control	IUGR	IUGR	Age	Interaction
Birth weight (g)	6.14 ± 0.03	4.99 ± 0.25*	6.43 ± 0.28	4.55 ± 0.20*	-	-	-
BW (g)	248.9 ± 2.6	248.5 ± 7.8	285.3 ± 3.0†	279.1 ± 11.1†	ns	P<0.001	ns
Total body fat (g)/BW (g)	0.091 ± 0.009	0.087 ± 0.006	0.104 ± 0.006	0.142 ± 0.015†‡	ns	P<0.01	ns
Total lean mass (g)/BW (g)	0.854± 0.008	0.865 ± 0.017	0.786± 0.028	0.689 ± 0.029†‡	ns	P<0.01	ns
Total body water (g)/BW (g)	0.657± 0.010	0.659 ± 0.020	0.607± 0.010	0.505 ± 0.021†‡	ns	P<0.05	P<0.05
Visceral fat (g)/BW (kg)	2.12± 0.4	3.08 ± 1.1	11.2± 1.8†	23.6 ± 4.7†‡	P<0.001	P<0.01	P<0.05
Food intake (g)/BW (g)/day	0.064± 0.008	0.042 ± 0.009	0.045± 0.006	0.041 ± 0.006	ns	ns	ns
Water intake (g)/BW (g)/day	0.112± 0.008	0.075 ± 0.021	0.104± 0.009	0.074 ± 0.009	P<0.05	ns	ns
24 hrs urinary excretion (ml)	12.8± 1.2	14.4 ± 3.1	20.5± 2.3	13.6 ± 1.7	ns	ns	ns

Intrauterine growth restriction (IUGR). Values are the mean ± S.E.M., (n = 14 rats per group).

^*P<0.05 vs. control using unpaired t-test.

P values the significance in the effect for the respective source of variation (IUGR or age) using two-way ANOVA;

^†P<0.05 in Bonferroni post hoc test comparing age matched control and IUGR offspring.

^‡P < 0.05 Bonferroni post hoc test comparing same group in different age.