Fig 1.
Magnitude and immunodominance of antibody and T cell responses are similar between wP- and aP-primed cohorts. (A) Sum of titers across all aP antigens from each donor in wP/no boost and aP/no boost cohorts, as assayed by ELISA. (B) Immunodominance of antigens in both cohorts expressed as the percentage of the total response. (C) Overall responses against aP peptides as measured by dual color ELISPOT. Each data point represents the sum of responses across all aP antigens for a single wP/no boost or aP/no boost donor. (D) Immunodominance of each antigen is expressed as percentage of the total T cell response in wP and aP cohorts. Data is expressed as median ± interquartile range for each cohort. *: p < 0.05, ns, no significant difference by Mann-Whitney test.