Table 1.
Study | Year | Statistical measure | No. | Conclusions |
---|---|---|---|---|
Benninger et al. [13] | 1997 | Proportion (11 %)* | 100 | Endoscopy useful only when diagnosis unclear |
Rosbe et al. [14] | 1998 | Proportion (91 %)** | 92 | High specificity of endoscopy |
Stankiewicz et al. [11] | 2002 | Sensitivity (46 %), specificity (86 %), PPV (74 %), NPV (64 %) | 78 | Low correlation with subjective symptoms, high specificity of endoscopy |
Bhattacharyya et al. [12] | 2010 | PPV (66.0), NPV (70.3), OR (4.6) | 202 | Addition of endoscopy to subjective symptoms greatly improved the diagnostic accuracy |
Ferguson et al. [15] | 2012 | Sensitivity (24 %), specificity (100 %) | 125 | High specificity and low sensitivity of endoscopy make it useful for confirming CRS diagnosis but not for ruling it out |
Present study | 2014 | Sensitivity (88.04 %), sensitivity (28.57 %), PPV (94.19 %), NPV (15.38 %), PLR (1.23), NLR (0.42), p value (0.10565) | 100 | High sensitivity and PPV makes endoscopy a diagnostic modality to accurately diagnose the disease but does not rule it out |
PPV positive predictive value, NPV negative predictive value, OR odds ratio
* Proportion in Benninger et al. [13] study means proportion of participants in whom nasal endoscopy played an important role in the evaluation when added to history and physical examination with anterior rhinoscopy
** Proportion in Rosbe et al. [14] study indicates proportion of participants with positive endoscopy findings who also had computed tomography positive for CRS