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TSA on pooled result of ASES score is shown. The RIS of 1306 patients was estimated using α = 0.05 (two sided), β = 0.20 (power 80 %) and the empirical data autogenerated from software according to the data input. The cumulative Z-curve crossed the conventional boundary, but neither the trial sequential monitoring boundary nor the RIS line was surpassed. RIS required information size, TSA trial sequential analysis, ASES American Shoulder and Elbow Surgeons
