Table 3.
Comparision of dosimetric metrics of OARs as a function of plan modality ( ± SD)
| Metric | 3DCRT | for-IMRT | inv-IMRT | HT | VMAT | p-value |
|---|---|---|---|---|---|---|
| Heart (RB) | ||||||
| Dmax (Gy) | 2.73 ± 0.56 | 2.73 ± 0.52 | 17.80 ± 5.46 | 15.65 ± 3.38 | 12.87 ± 2.15 | <0.001 |
| Dmean (Gy) | 0.95 ± 0.17 | 0.93 ± 0.15 | 5.10 ± 1.20 | 3.74 ± 0.92 | 4.99 ± 0.76 | <0.001 |
| V5 (%) | 0.0 ± 0.0 | 0.0 ± 0.0 | 39.50 ± 19.02 | 27.60 ± 15.16 | 38.00 ± 12.10 | <0.001 |
| V10 (%) | 0.0 ± 0.0 | 0.0 ± 0.0 | 7.00 ± 4.26 | 3.50 ± 3.42 | 3.90 ± 2.95 | <0.001 |
| LAD (RB) | ||||||
| Dmax (Gy) | 1.00 ± 0.13 | 1.01 ± 0.16 | 8.10 ± 3.42 | 6.54 ± 1.85 | 4.63 ± 0.83 | <0.001 |
| Dmean (Gy) | 0.85 ± 0.20 | 0.81 ± 0.10 | 5.05 ± 1.56 | 3.49 ± 1.20 | 3.71 ± 0.67 | <0.001 |
| Ipsilateral lung | ||||||
| Dmax (Gy) | 51.50 ± 1.82 | 50.56 ± 1.34 | 45.96 ± 2.52 | 43.13 ± 4.32 | 44.26 ± 3.15 | <0.001 |
| Dmean (Gy) | 7.66 ± 2.50 | 7.49 ± 2.44 | 12.18 ± 3.21 | 4.93 ± 1.45 | 11.71 ± 3.47 | <0.001 |
| V5 (%) | 19.80 ± 7.12 | 12.93 ± 4.70 | 79.92 ± 13.02 | 49.40 ± 15.51 | 76.38 ± 20.37 | <0.001 |
| V10 (%) | 15.21 ± 5.05 | 15.22 ± 5.22 | 44.26 ± 20.71 | 20.92 ± 6.58 | 40.30 ± 16.07 | <0.001 |
| V20 (%) | 12.99 ± 4.60 | 12.93 ± 4.70 | 15.64 ± 7.37 | 6.91 ± 2.03 | 14.69 ± 5.52 | 0.005 |
| Contralateral lung | ||||||
| Dmax (Gy) | 1.52 ± 0.38 | 1.58 ± 0.37 | 11.67 ± 3.30 | 11.49 ± 4.22 | 6.25 ± 1.30 | <0.001 |
| Dmean (Gy) | 0.35 ± 0.08 | 0.35 ± 0.08 | 3.69 ± 1.13 | 2.46 ± 0.96 | 2.50 ± 0.57 | <0.001 |
| V5 (%) | 0.0 ± 0.0 | 0.0 ± 0.0 | 25.75 ± 18.43 | 14.16 ± 11.82 | 2.46 ± 4.55 | <0.001 |
| V10 (%) | 0.0 ± 0.0 | 0.0 ± 0.0 | 1.73 ± 2.27 | 1.41 ± 2.43 | 0.0 ± 0.0 | 0.016 |
| Contralateral breast | ||||||
| Dmax (Gy) | 2.53 ± 0.91 | 2.66 ± 0.99 | 7.90 ± 2.76 | 9.68 ± 1.88 | 9.58 ± 2.99 | <0.001 |
| Dmean (Gy) | 0.54 ± 0.14 | 0.53 ± 0.14 | 2.69 ± 0.78 | 2.96 ± 0.57 | 2.19 ± 0.49 | <0.001 |
| V3 (%) | 0.16 ± 0.31 | 0.17 ± 0.36 | 27.87 ± 15.98 | 48.72 ± 15.42 | 17.80 ± 8.79 | <0.001 |
| V5 (%) | 0.0 ± 0.0 | 0.0 ± 0.0 | 6.25 ± 6.98 | 14.54 ± 7.06 | 3.84 ± 3.87 | <0.001 |
| Body-PTV | ||||||
| V3 (%) | 7.81 ± 3.35 | 7.86 ± 3.05 | 51.98 ± 11.50 | 39.30 ± 10.30 | 40.77 ± 9.68 | <0.001 |
| V5 (%) | 5.76 ± 2.38 | 5.73 ± 2.23 | 34.57 ± 9.10 | 27.19 ± 8.31 | 25.79 ± 7.98 | <0.001 |
| V10 (%) | 4.53 ± 1.96 | 4.52 ± 1.88 | 15.32 ± 4.46 | 13.86 ± 4.66 | 11.69 ± 4.11 | <0.001 |
| V20 (%) | 3.45 ± 1.62 | 3.41 ± 1.59 | 4.91 ± 1.68 | 5.95 ± 2.24 | 4.67 ± 1.91 | 0.016 |
| V30 (%) | 2.80 ± 1.43 | 2.77 ± 1.42 | 1.92 ± 0.88 | 2.39 ± 1.07 | 1.66 ± 0.85 | 0.124 |
D max max dose, D mean mean dose, V x volume (%) receiving x dose (Gy) or higher