Fig. 5.

Chordoma and chondrosarcoma. (A–C) A 67-year-old-male with a chordoma that was initially diagnosed at the age of 55 (A, sagittal MRI). He underwent multiple resections for tumor recurrences. Twelve years after the original diagnosis and 2 years after “complete” surgical resection, he presented with a large, infiltrative recurrence (B and C, axial and coronal MRIs, respectively). Notice the tumor extension into the ethmoid sinuses, cavernous sinus and right orbit. (D–F) 37-year-old-female with progressive right cranial nerve deficits (III, VI, VII and VIII) was found to have a skull base chondrosarcoma. Axial MRI pre- (D) and axial and coronal MRIs postcontrast (E and F) show the skull base mass lesion. These lesions required repeated extradural middle cranial fossa approaches for tumor control. Used with permission from Barrow Neurological Institute.