Table 2.
Correlation between HO-1, BMP-7, Runx2, and other biomarkers in patients with RA and AS. Correlations were performed using Spearman's correlation coefficient (r s).
| RA (r s) | AS (r s) | |||||
|---|---|---|---|---|---|---|
| HO-1 | BMP-7 | Runx2 | HO-1 | BMP-7 | Runx2 | |
| HO-1 | 0.392∗ | 0.403∗∗ | 0.499∗∗ | −0.029 | ||
| BMP-7 | 0.392∗ | 0.352∗ | 0.499∗∗ | −0.131 | ||
| Runx2 | 0.403∗∗ | 0.352∗ | −0.029 | −0.131 | ||
| NMID | 0.007 | 0.067 | −0.328∗ | −0.023 | −0.272 | 0.447∗∗ |
| BALP | 0.201 | 0.116 | −0.115 | −0.249 | −0.319 | 0.097 |
| CTX | 0.247 | 0.209 | −0.069 | 0.106 | −0.255 | 0.328 |
| TRAP-5b | 0.337∗ | 0.562∗∗ | 0.134 | −0.127 | −0.384∗ | 0.301 |
∗ p < 0.05; ∗∗ p < 0.01. RA: rheumatoid arthritis; AS: ankylosing spondylitis; HO-1: heme oxygenase-1; BMP-7: bone morphogenetic protein-7; Runx2: Runt related-transcription factor 2; NMID: N-terminal midfragment of osteocalcin; BALP: bone alkaline phosphatase; CTX: C-terminal telopeptide of type I collagen; TRAP-5b: tartrate-resistant acid phosphatase-5b.