Table 6.
Study authors and year | Summary of results (summaries are based on descriptions in abstracts and articles) |
Performance |
---|---|---|
Pearce et al. 2013 [51] | Electrochemical endpoint assay prototype: a single card performs target DNA extraction, amplification, and electrochemical detection via electrochemical endpoint detection. This prototype is designed to work with the Atlas io platform | Sensitivity and specificity of 95.5% (42/44) and 95.7% (44/46), respectively Limit of detection: 5 TV cells No cross-reactivity with the nucleic acids from organisms commonly associated with the genitourinary tract |
| ||
Spizz et al. 2012 [47] | Rheonix CARD STI CARD assay: a patented lamination process incorporates all pumps, valves, microchannels, and reaction compartments into an inexpensive disposable plastic device that automatically performs all assay steps. Amplicons detected with Reverse Dot Blot assay | Able to detect a minimum of 10 copies of each of the four pathogens (N. gonorrhoeae, C. trachomatis, T. pallidum,and T. vaginalis) |