Table 2.
Steady-state delivery rates for the various channel geometries as compared to the desired dosing rate.
| Drug | Design | Flux mol m−2 s−1 | nmol/day | Desired dosing rate (nmol/day) | Lifetime (years) |
|---|---|---|---|---|---|
| Macugen | Snake | 2.68E − 06 | 0.579 | 6 | 1.042 |
| Leaf | 1.71E − 05 | 3.703 | 0.163 | ||
| Straight | 6.11E − 05 | 13.207 | 0.046 | ||
|
| |||||
| Lucentis | Snake | 1.86E − 06 | 0.401 | 0.3472 | 1.503 |
| Leaf | 1.19E − 05 | 2.567 | 0.235 | ||
| Straight | 4.24E − 05 | 9.157 | 0.066 | ||
|
| |||||
| Intravitreal Avastin | Snake | 1.12E − 06 | 0.241 | 0.279 | 2.500 |
| Leaf | 7.14E − 06 | 1.543 | 0.391 | ||
| Straight | 2.55E − 05 | 5.503 | 0.110 | ||
|
| |||||
| Fluocinolone acetonide | Snake | 2.05E − 06 | 0.444 | 237 | 1.359 |
| Leaf | 1.31E − 05 | 2.839 | 0.212 | ||
| Straight | 4.69E − 05 | 10.125 | 0.060 | ||