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. 2016 Jun 9;6:27216. doi: 10.1038/srep27216

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Copyright © 2016, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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The viruliferous and healthy female SBPHs were dissected when they reached the 4^th peak hatching period when ova were mature, and viruliferous and healthy ova samples, respectively, were collected and lysed. Differentially expressed proteins were quantified relatively using iTRAQ labeling (tags 113 and 114, respectively) and analyzed by LC-MS/MS. At the end of the study, we conducted a general bioinformatics analysis to provide a complete list of RSV-responsive proteins in the ova and verified some proteins by RT-qPCR.