Table 1. List of differentially expressed proteins in ova of SBPH after RSV infection.
| Accession numbera | Proteins | Unique peptidesb | Sequence coverage [%]c | Ratiod |
|---|---|---|---|---|
| Translation | ||||
| 662195687 | eukaryotic translation initiation factor 2 subunit 3-like | 1 | 17.4 | 2.484511 |
| 662197941 | translationally controlled tumor protein homolog | 1 | 6.8 | 2.067828 |
| 641661996 | transcription elongation factor B polypeptide 2 | 1 | 6.9 | 1.984711 |
| 662206187 | eukaryotic peptide chain release factor GTP-binding subunit ERF3A | 1 | 4.5 | 1.830048 |
| 187123194 | ribosomal protein L24 | 1 | 8.3 | 1.785167 |
| 648215847 | 40S ribosomal protein S5 | 2 | 8.8 | 1.604823 |
| 662201329 | 40S ribosomal protein S23 | 2 | 8.4 | 1.528438 |
| 641647602 | 60S ribosomal protein L21-like | 2 | 12.7 | 1.51912 |
| 187115160 | ribosomal protein S17 | 1 | 10.8 | 1.457962 |
| 193580101 | 40S ribosomal protein S9 | 1 | 16.2 | 1.431053 |
| 662197167 | eukaryotic translation initiation factor 5A | 1 | 5 | 1.415218 |
| 662199441 | elongation factor Tu, mitochondrial-like | 1 | 2.7 | 1.406708 |
| 662207737 | 60S ribosomal protein L11 | 1 | 13 | 1.379142 |
| 662209085 | 60S ribosomal protein L8 | 3 | 14.4 | 1.369597 |
| 662209707 | 60S ribosomal protein L12 | 1 | 5.5 | 1.350648 |
| 662184235 | 40S ribosomal protein S11 | 2 | 7.2 | 1.33406 |
| 662218739 | 60S ribosomal protein L4-B-like, partial | 2 | 12.5 | 1.324579 |
| 187129222 | ribosomal protein L34 | 1 | 6.7 | 1.317411 |
| 662186416 | 40S ribosomal protein SA | 1 | 5.6 | 1.295956 |
| 662210930 | 60S ribosomal protein L23 | 1 | 7.1 | 1.270119 |
| 187129228 | 40S ribosomal protein S25 | 2 | 9.5 | 1.266763 |
| 641679542 | heterogeneous nuclear ribonucleoprotein 27C-like | 2 | 5.6 | 1.252255 |
| 662200191 | 60S ribosomal protein L32-like | 1 | 7.5 | 1.221087 |
| 240849131 | ribosomal protein S6 | 1 | 3.6 | 1.211985 |
| 641673750 | ribosomal protein S28e-like | 2 | 32.3 | 0.815808 |
| 662208447 | eukaryotic initiation factor 4A-I-like | 1 | 4.2 | 0.780624 |
| 641662274 | eukaryotic translation initiation factor 3 subunit C | 1 | 1.5 | 0.700217 |
| 662224988 | 40S ribosomal protein S8-like, partial | 1 | 25.9 | 0.658957 |
| Metabolism | ||||
| 662219845 | persulfide dioxygenase ETHE1, mitochondrial | 1 | 3.2 | 6.127282 |
| 328697388 | 2-oxoglutarate dehydrogenase, mitochondrial | 1 | 1.4 | 1.652311 |
| 641677413 | UDP-N-acetylglucosamine–peptide N-acetylglucosaminy-ltransferase-like | 1 | 1.7 | 1.524594 |
| 641654954 | V-type proton ATPase catalytic subunit A | 1 | 8.5 | 1.512928 |
| 328704972 | delta-1-pyrroline-5-carboxylate synthase | 4 | 7.9 | 1.448002 |
| 328700405 | proline dehydrogenase 1, mitochondrial | 1 | 3.6 | 1.341319 |
| 328697410 | DEAD-box ATP-dependent RNA helicase 20-like | 2 | 4.2 | 1.32052 |
| 662214999 | glutamate dehydrogenase, mitochondrial-like | 2 | 5.3 | 1.302101 |
| 662210960 | 1,4-alpha-glucan-branching enzyme-like | 1 | 6.2 | 1.27316 |
| 193700143 | aldehyde dehydrogenase, mitochondrial | 2 | 2.9 | 1.271559 |
| 662192943 | pyruvate carboxylase, mitochondrial-like | 4 | 3.9 | 1.218207 |
| 641675019 | UTP–glucose-1-phosphate uridylyltransferase-like | 2 | 4.2 | 1.207656 |
| 193580190 | isocitrate dehydrogenase [NADP] cytoplasmic-like | 2 | 4.9 | 1.20412 |
| 641659015 | T-complex protein 1 subunit zeta | 1 | 1.3 | 0.8241 |
| 641679894 | probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial | 1 | 2.5 | 0.814525 |
| 328710078 | 6-phosphogluconate dehydrogenase, decarboxylating | 2 | 3.9 | 0.81438 |
| 662210162 | probable 3-hydroxyacyl-CoA dehydrogenase B0272.3 | 1 | 3 | 0.793047 |
| 662201252 | phosphoglycerate kinase | 1 | 4.5 | 0.791029 |
| 662193985 | acetyl-CoA carboxylase-like | 3 | 2.9 | 0.769906 |
| 662207937 | glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic-like | 1 | 3.4 | 0.744568 |
| 328713184 | very long-chain specific acyl-CoA dehydrogenase, mitochondrial | 1 | 1.7 | 0.718995 |
| 193669238 | translation initiation factor eIF-2B subunit delta | 1 | 2.1 | 0.701824 |
| 328700025 | 6-phosphofructokinase | 1 | 1.1 | 0.696162 |
| 641647799 | histidine decarboxylase | 1 | 2 | 0.689838 |
| 662205392 | malate dehydrogenase, mitochondrial-like ; | 2 | 16.9 | 0.67347 |
| 662195667 | ribose-phosphate pyrophosphokinase 1 | 1 | 4.9 | 0.632195 |
| Electron transport | ||||
| 662201650 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial-like | 1 | 9.2 | 1.359605 |
| 671729049 | cytochrome c oxidase subunit II (mitochondrion) | 1 | 3.6 | 1.350648 |
| 662197766 | electron transfer flavoprotein subunit beta-like | 1 | 22.5 | 1.320515 |
| 662187693 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | 1 | 2.7 | 1.220327 |
| Response | ||||
| 662204299 | RACK1 guanine nucleotide-binding protein subunit beta-like protein | 1 | 3.8 | 2.009609 |
| 662194343 | guanine nucleotide-binding protein G(o) subunit alpha | 1 | 3.7 | 1.984605 |
| 662191009 | ras-related protein Rab6-like | 2 | 13.9 | 1.652277 |
| 641673378 | aldehyde dehydrogenase-like | 1 | 2 | 1.569280 |
| 662216228 | transitional endoplasmic reticulum ATPase TER94-like | 1 | 3.6 | 1.492503 |
| 193587299 | heat shock protein 70 B2-like | 1 | 8.2 | 1.414212 |
| 662212992 | putative ATP-dependent RNA helicase me31b | 1 | 2.1 | 1.381543 |
| 328705845 | dentin sialophosphoprotein | 1 | 0.6 | 1.320508 |
| 662219635 | heat shock protein 83-like | 1 | 7.3 | 1.320508 |
| 662196678 | 26S protease regulatory subunit 8 | 4 | 12.4 | 1.267469 |
| 662199945 | protein transport protein Sec61 subunit alpha | 1 | 1.9 | 1.234578 |
| 662212366 | ankyrin repeat domain-containing protein 17 | 1 | 0.4 | 1.232153 |
| 662224369 | heat shock 70 kDa protein cognate 4-like, partial | 1 | 15 | 1.208884 |
| 662206271 | heat shock 70 kDa protein | 3 | 5.2 | 1.206334 |
| 662196490 | sodium/potassium-transporting ATPase subunit alpha-like, partial | 3 | 17.4 | 1.224616 |
| 193652521 | ATP-dependent RNA helicase WM6 | 1 | 2.4 | 0.696162 |
| Cell cycle | ||||
| 662198987 | serine/threonine-protein phosphatase 2B catalytic subunit 2-like | 1 | 15.2 | 1.984675 |
| 662183545 | titin-like | 1 | 0.2 | 1.585952 |
| 662198211 | cofilin/actin-depolymerizing factor homolog | 2 | 16.5 | 0.821183 |
| 187179329 | twinstar | 1 | 4.7 | 0.79105 |
| 662201759 | G2/mitotic-specific cyclin-B3-like | 1 | 1.9 | 0.61666 |
| 662211502 | AP-2 complex subunit alpha | 1 | 1.4 | 0.493967 |
| 662185744 | dynein heavy chain, cytoplasmic-like | 1 | 0.2 | 0.194088 |
| Transport | ||||
| 662197932 | ras-related protein Rab-2A | 1 | 9.4 | 1.984636 |
| 662183037 | plasma membrane calcium-transporting ATPase 3-like | 1 | 1.7 | 1.685486 |
| 326319966 | V-type proton ATPase subunit D | 1 | 2.6 | 1.486314 |
| 193634236 | innexin inx2 | 1 | 2.5 | 1.486244 |
| 328711155 | clathrin heavy chain | 2 | 1.9 | 1.439576 |
| 662224735 | V-type proton ATPase subunit E-like | 1 | 5.8 | 1.358345 |
| 662218609 | ADP-ribosylation factor 2-like, partial | 1 | 8.4 | 1.27316 |
| 662187312 | fatty acid-binding protein, muscle | 1 | 6.8 | 1.237659 |
| 187121188 | bicaudal | 1 | 6.6 | 0.815664 |
| 662190099 | apolipophorins-like | 1 | 0.3 | 0.802221 |
| 641657530 | glutamate receptor ionotropic, kainate 1 | 1 | 2 | 0.79105 |
| 662206445 | ras-related protein Rab-7a | 1 | 5.2 | 0.696162 |
| 641666000 | ATP-binding cassette sub-family E member 1 | 1 | 1.5 | 0.60393 |
| 662213752 | vacuolar protein sorting-associated protein 29 | 1 | 5.5 | 0.55669 |
| Transcription regulation | ||||
| 662211365 | forkhead box protein O-like, partial | 1 | 3.4 | 2.099884 |
| 641667108 | segmentation protein Runt-like | 1 | 2.1 | 1.364041 |
| 662221075 | histone H4 | 1 | 50.5 | 1.344955 |
| 328717963 | probable ATP-dependent RNA helicase DDX5 | 1 | 4 | 1.26917 |
| Signal transduction | ||||
| 662218361 | spectrin beta chain, erythrocytic-like, partial | 1 | 3.8 | 2.484511 |
| 240848699 | troponin C-like | 1 | 9.3 | 2.166203 |
| 648215987 | FK506-binding protein 1 precursor | 1 | 8.1 | 1.984675 |
| 641649210 | calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1C-like | 1 | 1 | 1.585871 |
| 662185726 | ras-related protein Rab-8B-like | 1 | 8.3 | 1.527754 |
| 662191522 | ralA-binding protein 1-like | 1 | 1.6 | 0.592953 |
| Others | ||||
| 641667476 | dystonin | 1 | 0.2 | 5.332768 |
| 193618005 | T-complex protein 1 subunit gamma-like | 1 | 2 | 2.317678 |
| 641657060 | trichohyalin-like | 1 | 2.9 | 2.127308 |
| 662221462 | zinc finger CCCH domain-containing protein 13-like, partial | 1 | 1.4 | 2.00459 |
| 641654607 | uncharacterized protein LOC103308150 | 1 | 5.1 | 1.984605 |
| 662206904 | uncharacterized protein LOC103513857, partial | 1 | 2.2 | 1.874966 |
| 641664858 | uncharacterized protein LOC100571486 | 1 | 1.5 | 1.805057 |
| 641679348 | zinc finger MYM-type protein 1-like | 1 | 1.1 | 1.65225 |
| 237874213 | Obg-like ATPase 1 | 1 | 2.5 | 1.616551 |
| 662198825 | uncharacterized protein LOC103509702 | 1 | 1.5 | 1.478131 |
| 641659614 | uncharacterized protein LOC103308837 | 1 | 0.7 | 1.457034 |
| 641658025 | uncharacterized protein LOC100573999 | 1 | 2.1 | 1.422523 |
| 662203311 | uncharacterized protein LOC103512009 | 1 | 2.1 | 1.409739 |
| 662199313 | T-complex protein 1 subunit theta | 2 | 4.7 | 1.355449 |
| 662224929 | troponin T-like | 2 | 5.7 | 1.29113 |
| 298676439 | tubulin beta-1 chain | 7 | 23.5 | 1.286363 |
| 641651626 | tubulin beta chain-like | 1 | 7.7 | 1.280335 |
| 328699232 | spectrin beta chain | 4 | 1.7 | 1.248244 |
| 641678036 | spectrin alpha chain | 2 | 4.2 | 1.238482 |
| 328708622 | muscle LIM protein Mlp84B-like | 2 | 4.8 | 1.231617 |
| 328709476 | multiple inositol polyphosphate phosphatase 1-like | 1 | 1.5 | 1.229761 |
| 328703083 | alpha-actinin, sarcomeric | 3 | 10.9 | 1.222747 |
| 662217109 | uncharacterized protein LOC103519217 | 1 | 1.3 | 1.200012 |
| 662199835 | neural-cadherin-like | 1 | 6.7 | 0.8241 |
| 328715019 | transketolase-like protein 2 | 1 | 2.1 | 0.819711 |
| 662194096 | paxillin | 1 | 4.8 | 0.810566 |
| 662187362 | GTP-binding protein 1-like | 1 | 4.6 | 0.803458 |
| 662199465 | lisH domain and HEAT repeat-containing protein KIAA1468 homolog | 1 | 1.2 | 0.784215 |
| 328702659 | uncharacterized protein LOC100569797 | 1 | 1.8 | 0.777457 |
| 328721582 | netrin-1-like | 1 | 5.4 | 0.776104 |
| 662204082 | myosin heavy chain, muscle-like | 3 | 12.2 | 0.77215 |
| 662198855 | immunoglobulin superfamily containing leucine-rich repeat protein 2-like | 1 | 4.3 | 0.768863 |
| 641646988 | 26S proteasome non-ATPase regulatory subunit 10-like | 1 | 8.9 | 0.738145 |
| 648216270 | uncharacterized protein LOC100168138 | 1 | 5.9 | 0.706124 |
| 641673054 | uncharacterized protein LOC103310269 | 1 | 2.9 | 0.702618 |
| 662218667 | uncharacterized protein LOC103520057 | 1 | 0.8 | 0.648129 |
| 662197467 | putative uncharacterized protein DDB_G0282133 | 1 | 0.6 | 0.635234 |
| 641668388 | microtubule-associated serine/threonine-protein kinase 3 | 1 | 0.7 | 0.55669 |
| 662219363 | uncharacterized protein MAL13P1.304-like, partial | 1 | 1.1 | 0.542914 |
| 662189113 | ubiquitin-like modifier-activating enzyme 1, partial | 1 | 1.4 | 0.449017 |
| 662208914 | uncharacterized protein LOC103514896 | 1 | 1.5 | 0.329166 |
| 662188243 | uncharacterized protein DDB_G0284459-like | 1 | 1.7 | 0.003 |
aProtein accession number from NCBI.
bNumber of unique peptides identified for each protein.
cPercentage sequence coverage of identified proteins.
dRatios of RSV-infected/mock-infected proteins.