Fig. 5.

Constitutively active NFATc1 induces MyHC-slow gene expression in regenerating denervated muscles. Serial sections of regenerating denervated soleus (A and B) and EDL (C and D) muscles cotransfected with caNFATc1 and GFP to identify transfected fibers. Sections were examined for GFP fluorescence (A and C) or stained with a monoclonal antibody specific for MyHC-slow (B and D). Note that most fibers expressing GFP stain for MyHC-slow unlike the surrounding untransfected fibers. (Bar = 50 μm.)